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This has been a goal of many people in the field of medical treatment of obesity, to achieve the same amount of weight loss as achieved by our surgical colleagues

Lilly, the developer of orforglipron, will release data on weight loss in people without diabetes later this year

We did not estimate a treatment-policy (all-exposed/intention-to-treat-like) effect, as this represents a different estimand and would require additional prespecified analytic assumptions to appropriately handle treatment modification and its potentially non-random occurrence in routine care

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But what makes peptide therapy so special